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Immune microniches shape intestinal Treg function

Mice C57BL/6 J (B6) and Foxp3GFP, Rag1−/−, CD2DsRed, Foxp3CD2Il10GFP, UbPA-GFP and Nur77GFP mice were bred and maintained under specific pathogen free

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Fossils document evolutionary changes of jaw joint to mammalian middle ear

Kermack, K. A., Mussett, F. & Rigney, H. W. The lower jaw of Morganucodon. Zool. J. Linn. Soc. 53, 87–175

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Mechanical activation opens a lipid-lined pore in OSCA ion channels

Hou, C. et al. DUF221 proteins are a family of osmosensitive calcium-permeable cation channels conserved across eukaryotes. Cell Res. 24,

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Phase-change memory via a phase-changeable self-confined nano-filament

Ambrogio, S. et al. Equivalent-accuracy accelerated neural-network training using analogue memory. Nature 558, 60–67 (2018). Article  ADS  CAS  PubMed  Google

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Improving prime editing with an endogenous small RNA-binding protein

General methods CRISPRi sgRNAs were cloned into pU6-sgRNA EF1Alpha-puro-T2A-BFP (Addgene, 60955)13 as described in https://weissman.wi.mit.edu/resources/sgRNACloningProtocol.pdf (Supplementary Table 4). Plasmids for

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Bridging structural and cell biology with cryo-electron microscopy

Berman, H., Henrick, K. & Nakamura, H. Announcing the worldwide Protein Data Bank. Nat. Struct. Biol. 10, 980 (2003). CAS 

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Metal telluride nanosheets by scalable solid lithiation and exfoliation

Zhou, J. et al. A library of atomically thin metal chalcogenides. Nature 556, 355–359 (2018). Article  ADS  CAS  PubMed  Google

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Tropical-forest destruction has slowed — but is still too high

Loss of pristine tropical forests slowed last year — but the world is still falling far short of a global

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The variation and evolution of complete human centromeres

Cell lines CHM1hTERT (CHM1) cells were originally isolated from a hydatidiform mole at Magee-Womens Hospital. Cryogenically frozen cells from this

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Heat flows enrich prebiotic building blocks and enhance their reactivity

List of substances used For a list of abbreviations, see Supplementary Table 1. Nucleobases A and T, nucleosides Ado, Guo