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NATURE

Jekyll and Hyde flip of the script when bacteria invert gene sequences

Random mutation is a powerful approach used by many organisms, including bacteria, to generate genomic changes that can lead to

NATURE

Pain researchers must learn from the opioid crisis

In 2022, more than 80,000 people died of an opioid overdose in the United States. To reduce this toll, we

NATURE

How a ‘pain-o-meter’ could improve treatments

A participant holds his hand in a bucket of ice while Yingzi Lin monitors his pain response.Credit: Ruby Wallau/Northeastern Univ.

NATURE

Bigger AI chatbots more inclined to spew nonsense — and people don’t always realize

A study of newer, bigger versions of three major artificial intelligence (AI) chatbots shows that they are more inclined to

NATURE

How pain is misunderstood and ignored in women

“Women are born with pain built in. It’s our physical destiny.” With those words, Kristin Scott Thomas’s character in the

NATURE

Phages reconstitute NAD+ to counter bacterial immunity

Millman, A. et al. An expanded arsenal of immune systems that protect bacteria from phages. Cell Host Microbe 30, 1556–1569

APPS

Instead of Notes, Napkin Wants to Help You Collect Good Ideas

Along with typing in ideas, you can also easily use your iPhone camera to snap a picture. Those are converted

NATURE

The type 2 cytokine Fc–IL-4 revitalizes exhausted CD8+ T cells against cancer

Animals Six- to eight-week-old female CD45.2+Thy1.2+ C57BL/6 (C57BL/6J) mice, CD45.1+ mice (B6.SJL-Ptprca Pepcb/BoyCrl) and NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice were purchased

RELIGION

Did Moses really die before entering the Promised Land?

(RNS) — I don’t normally quote two family members in one article, but since this is the season of forgiveness,

APPS

Gray Raven Gets a BLACK★ROCK SHOOTER Crossover Called Blazing Simulacrum

It’s a match made in neon heaven. BLACK★ROCK SHOOTER is a A-Rank Attacker Omniframe, which makes her obtainable within 10